INT267887

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.58

unfolded protein binding (St13) protein folding (St13) cytosol (St13) kinase activity (Insrr) protein complex (St13) cytoplasm (St13)

Anatomy Link Frequency primary neurons 2 St13 (Mus musculus) Insrr (Mus musculus)

Pain Link Frequency Relevance Heat Enkephalin 7 99.90 agonist 58 94.16 opioid receptor 7 52.56 Opioid 4 50.00 analgesia 2 27.16 Pain 14 11.44 tolerance 10 5.00 IPN 8 5.00 Spinal cord 5 5.00 Analgesic 5 5.00

Disease Link Frequency Relevance Heat Neuroblastoma 3 45.76 Pain 15 11.44 Inflammatory Pain 8 5.00 Targeted Disruption 6 5.00 Hyperalgesia 5 5.00 Neuropathic Pain 4 5.00 INFLAMMATION 2 5.00 Decapitation 1 5.00 Stress 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similarly, our initial examination of primary neurons from DOR-eGFP mice, showed that Met-enkephalin and SNC80 trigger rapid internalization of the fluorescent receptor [13].

SNC80 Positive_regulation (trigger) of Localization (internalization) of receptor in primary neurons associated with enkephalin

1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2672171 Disease Relevance 0 Pain Relevance 0.58

General Comments

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