INT267888

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.64

unfolded protein binding (St13) protein folding (St13) cytosol (St13) kinase activity (Insrr) protein complex (St13) cytoplasm (St13)

St13 (Mus musculus) Insrr (Mus musculus)

Pain Link Frequency Relevance Heat Enkephalin 7 98.72 agonist 58 94.12 opioid receptor 7 72.48 Opioid 4 50.00 analgesia 2 47.08 Pain 14 31.36 IPN 8 22.32 tolerance 10 5.00 Spinal cord 5 5.00 Analgesic 5 5.00

Disease Link Frequency Relevance Heat Neuroblastoma 3 65.68 Pain 15 31.36 Inflammatory Pain 8 22.32 Targeted Disruption 6 5.00 Hyperalgesia 5 5.00 Neuropathic Pain 4 5.00 INFLAMMATION 2 5.00 Decapitation 1 5.00 Stress 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

SNC80 and ARM390 therefore bind to and activate the DOR-eGFP receptor with comparable potencies and efficacies.

SNC80 Positive_regulation (activate) of receptor

1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2672171 Disease Relevance 0.07 Pain Relevance 0.64

General Comments

This test has worked.