INT268075

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Context Info
Confidence 0.59
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.42
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Tdo2)
Anatomy Link Frequency
liver 4
Tdo2 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 14 55.40 Quite High
antidepressant 6 37.96 Quite Low
Serotonin 8 25.96 Quite Low
Hippocampus 32 5.00 Very Low Very Low Very Low
Eae 20 5.00 Very Low Very Low Very Low
midbrain 8 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 76.28 Quite High
Neurodegenerative Disease 38 72.44 Quite High
Congenital Anomalies 4 72.16 Quite High
Anxiety Disorder 58 71.08 Quite High
Mental Disorders 6 61.76 Quite High
Autism 6 55.88 Quite High
Depression 14 55.40 Quite High
Tourette's Syndrome 4 54.92 Quite High
Disease 6 53.84 Quite High
Obesity 2 16.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The disruption of tdo was verified by the absence of tdo mRNA transcripts and TDO protein in the liver, as assessed by quantitative real-time PCR and Western blot analyses, respectively (Figure 1D and 1E).
Negative_regulation (absence) of Transcription (transcripts) of tdo in liver
1) Confidence 0.59 Published 2009 Journal Mol Brain Section Body Doc Link PMC2673217 Disease Relevance 0.71 Pain Relevance 0.03
The disruption of tdo was verified by the absence of tdo mRNA transcripts and TDO protein in the liver, as assessed by quantitative real-time PCR and Western blot analyses, respectively (Figure 1D and 1E).
Negative_regulation (absence) of Transcription (transcripts) of TDO protein in liver
2) Confidence 0.43 Published 2009 Journal Mol Brain Section Body Doc Link PMC2673217 Disease Relevance 0.71 Pain Relevance 0.03

General Comments

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