INT268087

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Tyrp1) signal transduction (Gpr35) oxidoreductase activity (Tyrp1)
plasma membrane (Gpr35) signal transducer activity (Gpr35)
Anatomy Link Frequency
plasma 1
Tyrp1 (Mus musculus)
Gpr35 (Mus musculus)
Pain Link Frequency Relevance Heat
midbrain 4 80.84 Quite High
Hippocampus 16 80.32 Quite High
Eae 10 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
antidepressant 3 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 29 50.00 Quite Low
Neurodegenerative Disease 19 50.00 Quite Low
Depression 7 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Autism 3 5.00 Very Low Very Low Very Low
Mental Disorders 3 5.00 Very Low Very Low Very Low
Tourette's Syndrome 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to our findings for Trp, plasma levels of Kyn and KYNA, which are downstream Trp metabolites generated by TDO (Figure 1), were sustained at physiological levels despite the absence of TDO.
Trp Binding (findings) of KYNA in plasma
1) Confidence 0.02 Published 2009 Journal Mol Brain Section Body Doc Link PMC2673217 Disease Relevance 0 Pain Relevance 0.08

General Comments

This test has worked.

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