INT26813

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Context Info
Confidence 0.57
First Reported 1988
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.72
Pain Relevance 2.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OXT) extracellular space (OXT) extracellular region (OXT)
response to stress (OXT) cytoplasm (OXT)
OXT (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 10 100.00 Very High Very High Very High
narcan 24 99.98 Very High Very High Very High
Endogenous opioid 7 99.98 Very High Very High Very High
Nicotine 4 99.68 Very High Very High Very High
Opioid 5 96.80 Very High Very High Very High
antagonist 3 96.52 Very High Very High Very High
tolerance 1 93.60 High High
Disease Link Frequency Relevance Heat
Hypoglycemia 5 98.92 Very High Very High Very High
Nicotine Addiction 5 92.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endogenous opioids inhibit oxytocin release during nicotine-stimulated secretion of vasopressin in man.
Negative_regulation (inhibit) of Localization (release) of oxytocin associated with nicotine and endogenous opioid
1) Confidence 0.57 Published 1988 Journal Clin. Endocrinol. (Oxf) Section Title Doc Link 3214943 Disease Relevance 0.38 Pain Relevance 0.73
Endogenous opioids do not play an important role in the suppression of OT release when AVP is secreted in response to an osmotic stimulus in man.
Negative_regulation (suppression) of Localization (release) of OT associated with endogenous opioid
2) Confidence 0.41 Published 1989 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 2605788 Disease Relevance 0 Pain Relevance 0.45
Naloxone abolishes the inhibiting effect of somatostatin on the release of oxytocin evoked by insulin-induced hypoglycemia in humans.
Negative_regulation (abolishes) of Localization (release) of oxytocin associated with hypoglycemia, somatostatin and narcan
3) Confidence 0.37 Published 1989 Journal Metab. Clin. Exp. Section Title Doc Link 2569658 Disease Relevance 0.34 Pain Relevance 0.94
Endogenous opioids inhibit the release of oxytocin (OT) when vasopressin (AVP) is secreted in response to acute pharmacological stimuli in man and to a variety of physiological and pharmacological stimuli to animals.
Negative_regulation (inhibit) of Localization (release) of OT associated with endogenous opioid
4) Confidence 0.36 Published 1989 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 2605788 Disease Relevance 0 Pain Relevance 0.33

General Comments

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