INT268158

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Erc1) Golgi apparatus (Erc1) cytoplasm (Erc1)
Erc1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 70.52 Quite High
Amyloid Plaque 1 68.88 Quite High
Infection 8 49.68 Quite Low
Scrapie 13 27.12 Quite Low
Creutzfeldt Jakob Disease 8 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, by inhibiting PrP exit from the ERC using the Rab11 dominant-negative mutant, we found an increase in PrPSc levels, supporting the hypothesis that prion accumulation in the ERC stimulates PrPSc production.
Positive_regulation (stimulates) of Positive_regulation (accumulation) of ERC
1) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2673690 Disease Relevance 0.20 Pain Relevance 0

General Comments

This test has worked.

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