INT268189

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Gpi1, Erc1) isomerase activity (Gpi1) transport (Erc1)
Golgi apparatus (Erc1) carbohydrate metabolic process (Gpi1) cytosol (Gpi1)
Gpi1 (Mus musculus)
Erc1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 58.80 Quite High
Amyloid Plaque 1 57.16 Quite High
Infection 8 50.16 Quite High
Scrapie 13 15.40 Low Low
Creutzfeldt Jakob Disease 8 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the observation that cholesterol redistribution from other cellular compartments to LEs, induced by U18666A treatment, impairs PrP trafficking from EEs to the ERC (Figure 2C) suggests that cholesterol is not only important for GPI-AP retention within the ERC, but might also be required for its sorting from EEs to the ERC.
GPI-AP Binding (retention) of ERC
1) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2673690 Disease Relevance 0.17 Pain Relevance 0

General Comments

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