INT268312

Context Info Confidence 0.26 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.31 Pain Relevance 0

endosome (Slc2a4) transport (Slc2a4) transmembrane transporter activity (Slc2a4) plasma membrane (Slc2a4) transmembrane transport (Slc2a4) cytoplasm (Slc2a4)

Slc2a4 (Mus musculus)

Pain Link Frequency Relevance Heat ischemia 2 5.00 Inflammation 2 5.00 metalloproteinase 2 5.00 cytokine 1 5.00 anesthesia 1 5.00 Inflammatory response 1 5.00 tolerance 1 5.00 Kinase C 1 5.00

Disease Link Frequency Relevance Heat Insulin Resistance 7 99.60 Weight Gain 5 57.48 Stress 3 52.08 Shock 3 51.04 Obesity 48 50.00 Adhesions 5 12.64 Apoptosis 7 5.00 Hyperglycemia 5 5.00 Metabolic Syndrome 4 5.00 Pathologic Neovascularization 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This resulted in the insulin resistance marked by the down-regulation of insulin receptor signalling (Irs1, Foxo1, and Foxo3a), and down-regulation of Glut4.

Negative_regulation (regulation) of Negative_regulation (regulation) of Glut4 associated with insulin resistance

1) Confidence 0.26 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2674043 Disease Relevance 0.31 Pain Relevance 0

General Comments

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