INT268372

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Context Info
Confidence 0.81
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.39
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APC) chromosome organization (APC) cell adhesion (APC)
plasma membrane (APC) cytoskeleton (APC) nucleus (APC)
Anatomy Link Frequency
liver 1
APC (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 6 99.48 Very High Very High Very High
cINOD 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 152 100.00 Very High Very High Very High
Liver Cancer 10 99.60 Very High Very High Very High
Cirrhosis 9 99.48 Very High Very High Very High
Cancer 100 97.72 Very High Very High Very High
Metastasis 13 92.48 High High
Polyps 35 90.36 High High
Hyperplasia 16 90.04 High High
Fibrosis 4 89.08 High High
Hepatocellular Cancer 51 87.76 High High
Adenoma 34 82.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
APC promoter methylation in other liver tumors
Phosphorylation (methylation) of APC in liver associated with liver cancer and familial adenomatous polyposis
1) Confidence 0.81 Published 2007 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2757596 Disease Relevance 2.28 Pain Relevance 0.09
Another form of FAP is the attenuated APC variant, known as AAPC.
Phosphorylation (form) of APC associated with familial adenomatous polyposis
2) Confidence 0.54 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 1.11 Pain Relevance 0
In the absence of Wnt ligands, a complex containing APC, AXIN and GSK3 phosphorylates ?
Phosphorylation (phosphorylates) of APC
3) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813871 Disease Relevance 0 Pain Relevance 0

General Comments

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