INT268384

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SMAD3) nucleoplasm (SMAD3) transport (SMAD3)
plasma membrane (SMAD3) nucleus (SMAD3) intracellular (SMAD3)
SMAD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 62 87.92 High High
Apoptosis 10 85.64 High High
Pancreatic Cancer 2 73.96 Quite High
Colorectal Cancer 100 68.96 Quite High
Familial Adenomatous Polyposis 96 43.16 Quite Low
Hyperplasia 30 42.80 Quite Low
Adenoma 66 32.16 Quite Low
Targeted Disruption 4 26.04 Quite Low
Metastasis 4 13.44 Low Low
Syndrome 76 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This causes phosphorylation of SMAD2 and SMAD3, two transcription factors that then bind to and activate SMAD4.
Positive_regulation (causes) of Phosphorylation (phosphorylation) of SMAD3
1) Confidence 0.29 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 0.61 Pain Relevance 0
This causes phosphorylation of SMAD2 and SMAD3, two transcription factors that then bind to and activate SMAD4.
Positive_regulation (activate) of Phosphorylation (phosphorylation) of SMAD3
2) Confidence 0.21 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 0.62 Pain Relevance 0

General Comments

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