INT268396

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.72
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Ebp) cytosol (BRAF) endoplasmic reticulum (Ebp)
plasma membrane (BRAF) nucleus (BRAF) cytoplasm (BRAF)
BRAF (Homo sapiens)
Ebp (Mus musculus)
BRAF - V600E (1)
Pain Link Frequency Relevance Heat
COX2 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 31 97.28 Very High Very High Very High
Cleidocranial Dysplasia 2 94.80 High High
Polyps 35 93.92 High High
Adenoma 33 92.00 High High
Colon Cancer 4 89.28 High High
Hyperplasia 15 86.84 High High
Hereditary Nonpolyposis Colorectal Neoplasms 11 79.68 Quite High
Colorectal Cancer 50 58.64 Quite High
Malignant Neoplastic Disease 8 45.48 Quite Low
Carcinoma 16 43.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BRAF mutation V600E is associated with somatic mismatch repair deficiency (MSI) and found in 40% of the cases while in mismatch repair proficient tumors (MSS) the frequency is around 5%.
BRAF (V600E) Binding (associated) of MSI associated with cancer
1) Confidence 0.01 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 1.72 Pain Relevance 0

General Comments

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