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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Kras, ARAF) cytosol (ARAF) protein modification process (ARAF)
signal transduction (Kras) plasma membrane (Kras) GTPase activity (Kras)
Kras (Mus musculus)
ARAF (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 8 98.68 Very High Very High Very High
Carcinoma 16 87.40 High High
Colorectal Cancer 50 86.16 High High
Cancer 31 78.08 Quite High
Polyps 35 77.60 Quite High
Hyperplasia 15 71.84 Quite High
Adenoma 33 70.52 Quite High
Familial Adenomatous Polyposis 48 61.92 Quite High
Targeted Disruption 2 60.36 Quite High
Adenocarcinoma 1 43.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There are three RAF genes that encode serine/threonine kinases that are regulated by binding to RAS [119, 120].
RAS Binding (binding) of Regulation (regulated) of RAF
1) Confidence 0.03 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 1.16 Pain Relevance 0

General Comments

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