INT268398

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (LRP1, Wnt2) plasma membrane (LRP1, Wnt2) endosome (LRP1)
aging (LRP1) cell-cell signaling (Wnt2) cell proliferation (LRP1)
LRP1 (Homo sapiens)
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 48 86.40 High High
Colorectal Cancer 50 50.00 Quite Low
Cleidocranial Dysplasia 2 43.12 Quite Low
Malignant Neoplastic Disease 8 40.80 Quite Low
Cancer 31 39.16 Quite Low
Chromosomal Instability 3 33.64 Quite Low
Syndrome 38 5.00 Very Low Very Low Very Low
Polyps 35 5.00 Very Low Very Low Very Low
Adenoma 33 5.00 Very Low Very Low Very Low
Carcinoma 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Wnt glycoprotein binds to the transmembrane receptor frizzled and low-density lipoprotein receptor-related protein LRP-5/6 which leads to phosphorlation of LRP by GSK-3 ?
LRP Binding (binds) of Wnt
1) Confidence 0.01 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 0.36 Pain Relevance 0

General Comments

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