INT268521

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (WNT1) extracellular space (WNT1) extracellular region (WNT1)
proteinaceous extracellular matrix (WNT1) plasma membrane (WNT1) cell-cell signaling (WNT1)
WNT1 (Homo sapiens)
MIR221 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 124 99.00 Very High Very High Very High
Apoptosis 22 97.80 Very High Very High Very High
Death 4 69.32 Quite High
Hyperplasia 1 37.32 Quite Low
Chronic Lymphoid Leukemia 7 5.00 Very Low Very Low Very Low
Prostate Cancer 6 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 5 5.00 Very Low Very Low Very Low
Adenocarcinoma 5 5.00 Very Low Very Low Very Low
Lung Cancer 5 5.00 Very Low Very Low Very Low
Carcinoma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was also found that miR-221 may target the WNT1 inducible signaling pathway protein 3 (WISP3) which is a tumor suppressor that has been shown to have inhibitory effects on cell proliferation and angiogenesis.
WNT1 Binding (target) of miR-221 associated with cancer
1) Confidence 0.02 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674802 Disease Relevance 1.36 Pain Relevance 0

General Comments

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