INT268595

Context Info Confidence 0.00 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.59 Pain Relevance 0

cytoplasm (Mirlet7a-1, RASGRP1) cell differentiation (RASGRP1) Golgi apparatus (RASGRP1) endoplasmic reticulum (RASGRP1) cytosol (RASGRP1) lipid binding (RASGRP1)

Mirlet7a-1 (Mus musculus) RASGRP1 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 1 5.00 addiction 1 5.00

Disease Link Frequency Relevance Heat Cancer 124 81.04 Adenocarcinoma 5 66.64 Lung Cancer 5 50.04 Stress 4 37.20 Chronic Lymphoid Leukemia 7 25.80 Apoptosis 22 25.44 Prostate Cancer 6 5.00 Lymphatic System Cancer 5 5.00 Death 4 5.00 Carcinoma 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Additionally, transfection of HepG2 cells with a let-7a precursor resulted in about 70% reduction of RAS.

Gene_expression (transfection) of let-7a Negative_regulation (reduction) of RAS

1) Confidence 0.00 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674802 Disease Relevance 0.59 Pain Relevance 0

General Comments

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