INT268621

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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.54
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Gsk3b) carbohydrate metabolic process (Gsk3b) protein complex (Gsk3b)
response to stress (Gsk3b) cytoplasm (Gsk3b) cytosol (Gsk3b)
Anatomy Link Frequency
brain 2
Gsk3b (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 15 73.76 Quite High
cerebral cortex 5 73.12 Quite High
imagery 15 66.00 Quite High
Eae 42 57.32 Quite High
depression 14 44.92 Quite Low
amygdala 4 42.96 Quite Low
fluoxetine 3 39.96 Quite Low
sSRI 2 39.48 Quite Low
medulla 6 34.80 Quite Low
corticosteroid 30 20.64 Low Low
Disease Link Frequency Relevance Heat
Stress 42 100.00 Very High Very High Very High
Disease 41 96.00 Very High Very High Very High
Anxiety Disorder 42 90.48 High High
Aggression 26 85.84 High High
Cognitive Disorder 16 83.32 Quite High
Targeted Disruption 28 81.44 Quite High
Infection 2 79.60 Quite High
Shock 22 78.44 Quite High
Parkinson's Disease 40 50.00 Quite Low
Death 37 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is known that social behavior is affected by an animals sentiment (e.g. familiarity and comfort within a given situation) [101], hence, the increased sensitivity to stress observed in GSK-3?
Positive_regulation (increased) of Localization (observed) of GSK-3 associated with stress
1) Confidence 0.40 Published 2009 Journal Mol Brain Section Body Doc Link PMC2785804 Disease Relevance 0.57 Pain Relevance 0.05
Our studies revealed an increase in cerebellar volume, but normal brain volume in GSK-3?
Positive_regulation (increase) of Localization (volume) of GSK-3 in brain
2) Confidence 0.40 Published 2009 Journal Mol Brain Section Body Doc Link PMC2785804 Disease Relevance 0.33 Pain Relevance 0.03
As early as 1 h after the MPP+ treatment, there was a marked decrease in phospho-Tyr216-GSK-3?
Positive_regulation (after) of Localization (decrease) of GSK-3
3) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2675062 Disease Relevance 0 Pain Relevance 0
The present study not only supports the importance of GSK3 kinases (including GSK3?
Positive_regulation (supports) of Localization (importance) of GSK3
4) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877100 Disease Relevance 0.65 Pain Relevance 0.14

General Comments

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