INT268627

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.70
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ptpn2, Gsk3b) nucleus (Ptpn2, Gsk3b) cell differentiation (Gsk3b)
phosphatase activity (Ptpn2) endoplasmic reticulum (Ptpn2) carbohydrate metabolic process (Gsk3b)
Ptpn2 (Mus musculus)
Gsk3b (Mus musculus)
Pain Link Frequency Relevance Heat
Substantia nigra 8 77.04 Quite High
ischemia 4 5.00 Very Low Very Low Very Low
dopaminergic neurodegeneration 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 80 100.00 Very High Very High Very High
Disease 46 88.00 High High
Death 74 83.92 Quite High
Toxicity 14 9.04 Low Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 10 5.00 Very Low Very Low Very Low
Shock 8 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MPTP activated GSK-3?
MPTP Positive_regulation (activated) of GSK-3 associated with parkinson's disease
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2675062 Disease Relevance 0.70 Pain Relevance 0.04
To further confirm that the MPTP treatment induced GSK-3?
MPTP Positive_regulation (induced) of GSK-3 associated with parkinson's disease
2) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2675062 Disease Relevance 1.00 Pain Relevance 0.04

General Comments

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