INT268633

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Casp3) peptidase activity (Casp3) mitochondrion (Casp3)
nucleus (Casp3) intracellular (Casp3) cytoplasm (Casp3)
Anatomy Link Frequency
neurons 2
Mpz (Mus musculus)
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Substantia nigra 4 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
dopaminergic neurodegeneration 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 40 50.00 Quite Low
Death 37 50.00 Quite Low
Drug Induced Neurotoxicity 5 34.96 Quite Low
Disease 23 5.00 Very Low Very Low Very Low
Toxicity 7 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The MPP+ treatment induced the activation of caspase-3 in TSM1 neurons up to 233.9% as compared to the untreated control of active caspase-3 content of TSM1 cells.
MPP Positive_regulation (induced) of Positive_regulation (activation) of caspase-3 in neurons
1) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2675062 Disease Relevance 0 Pain Relevance 0

General Comments

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