INT268694

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOR2) small molecule metabolic process (NCOR2) nucleolus (NCOR2)
nucleus (NCOR2) DNA binding (NCOR2)
NCOR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 4 62.16 Quite High
agonist 23 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 2 97.28 Very High Very High Very High
Cancer 112 85.96 High High
Disease 7 85.24 High High
Renal Cancer 55 83.76 Quite High
Hematologic Neoplasms 1 81.44 Quite High
Adenocarcinoma 1 76.88 Quite High
Adhesions 6 70.80 Quite High
Lung Cancer 2 70.08 Quite High
Repression 17 69.36 Quite High
Hypoxia 7 65.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This correlates well with the observed changes in ANGPTL4 expression, pointing to a causal relationship between the regulation of class A genes and the recruitment of SMRT in response to TGF?
Regulation (regulation) of Gene_expression (recruitment) of SMRT
1) Confidence 0.42 Published 2011 Journal Nucleic Acids Research Section Body Doc Link PMC3017614 Disease Relevance 0.07 Pain Relevance 0
Recently, it has been shown that elevated SMRT levels result in suppression of target genes for the vitamin D receptor (VDR) in prostate cancer cells and in apparent hormonal insensitivity (Khanim et al. 2004).
Regulation (result) of Gene_expression (levels) of SMRT associated with reprotox - general 1
2) Confidence 0.35 Published 2007 Journal Cancer Informatics Section Body Doc Link PMC2675843 Disease Relevance 1.21 Pain Relevance 0.03

General Comments

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