INT268723

Context Info Confidence 0.01 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

cell differentiation (ROS1) cell proliferation (ROS1) extracellular region (PRB1) plasma membrane (ROS1) molecular_function (PRB1) biological_process (PRB1)

PRB1 (Homo sapiens) ROS1 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 10 5.00 Inflammation 9 5.00 Inflammatory response 2 5.00 imagery 1 5.00 qutenza 1 5.00

Disease Link Frequency Relevance Heat Stress 10 50.00 INFLAMMATION 11 5.00 Toxicity 5 5.00 Death 4 5.00 Injury 3 5.00 Pulmonary Disease 2 5.00 Heart Disease 1 5.00 Disease 1 5.00 Respiratory Disease 1 5.00 Cancer 1 5.00

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Key:

Protein

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Negation

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Since PM will contain large amounts of transition metals in their higher oxidation states, the use of the DTT assay with PM samples cannot be used to definitively indicate the formation of superoxide and other ROS as has been previously reported [24].

PM Binding (formation) of ROS

1) Confidence 0.01 Published 2009 Journal Part Fibre Toxicol Section Body Doc Link PMC2676242 Disease Relevance 0 Pain Relevance 0

General Comments

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