INT268766

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.40
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4, Ccr1) plasma membrane (Tlr4, Ccr1) intracellular (Tlr4)
cell-cell signaling (Ccr1) signal transducer activity (Ccr1) cytoplasm (Tlr4)
Anatomy Link Frequency
muscle cells 4
myotube 2
Tlr4 (Mus musculus)
Ccr1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 111 94.48 High High
Inflammatory response 6 88.80 High High
Inflammation 42 82.16 Quite High
cytokine 30 76.32 Quite High
Inflammatory stimuli 6 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 51 88.80 High High
Infection 45 86.40 High High
Adhesions 3 84.08 Quite High
Sepsis 78 59.20 Quite High
Endotoxemia 27 50.00 Quite Low
Pseudomonas Infection 12 38.28 Quite Low
Injury 18 5.00 Very Low Very Low Very Low
Frailty 9 5.00 Very Low Very Low Very Low
Respiratory Failure 6 5.00 Very Low Very Low Very Low
Peritonitis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that LPS-induced upregulation of RANTES expression in muscle cells involves an increased level of transcription from the RANTES promoter.
LPS Positive_regulation (upregulation) of Gene_expression (expression) of RANTES in muscle cells
1) Confidence 0.04 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2676322 Disease Relevance 0 Pain Relevance 0.03
construct prior to LPS stimulation at the myotube stage, there was a significant inhibition of subsequent LPS-induced RANTES expression, whereas IKK?
LPS Positive_regulation (induced) of Gene_expression (expression) of RANTES in myotube
2) Confidence 0.04 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2676322 Disease Relevance 0.40 Pain Relevance 0.20
These data suggest that LPS-induced upregulation of RANTES expression in muscle cells involves an increased level of transcription from the RANTES promoter.
LPS Positive_regulation (induced) of Gene_expression (expression) of RANTES in muscle cells
3) Confidence 0.04 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2676322 Disease Relevance 0 Pain Relevance 0.03

General Comments

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