INT268841

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Pitpnc1) signal transduction (Pitpnc1) transport (Pitpnc1)
nucleus (Pitpnc1) intracellular (Pitpnc1) cytoplasm (Pitpnc1)
Anatomy Link Frequency
Plasma 1
Pitpnc1 (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 18 5.00 Very Low Very Low Very Low
iatrogenic 15 5.00 Very Low Very Low Very Low
cryotherapy 3 5.00 Very Low Very Low Very Low
Taxol 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
backache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disorder Under Development 18 98.96 Very High Very High Very High
Cancer 78 96.72 Very High Very High Very High
Adenocarcinoma 3 95.80 Very High Very High Very High
Sarcoma 249 92.64 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 102 81.16 Quite High
Toxicity 18 64.76 Quite High
Disease 24 7.12 Low Low
Vomiting 12 5.00 Very Low Very Low Very Low
Alopecia 9 5.00 Very Low Very Low Very Low
Leukopenia 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These two properties combine to stabilize serum DNX, resulting in a half life between 4 and 5.6 h (t1/2 DNR ?
Gene_expression (resulting) of DNR
1) Confidence 0.10 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676651 Disease Relevance 0.34 Pain Relevance 0
Notably, as observed with other liposomal anthracycline formulations, cardiotoxicity is limited even in the presence of high cumulative DNR doses (?
Gene_expression (doses) of DNR associated with cardiovascular disorder under development
2) Confidence 0.10 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676651 Disease Relevance 0.56 Pain Relevance 0
Plasma DNR levels were consistently higher in DNX-treated mice compared with conventional DNR.
Gene_expression (levels) of DNR in Plasma
3) Confidence 0.10 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676651 Disease Relevance 0.49 Pain Relevance 0

General Comments

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