INT26890

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Context Info
Confidence 0.34
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.13
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (OGG1) mitochondrion (OGG1) lyase activity (OGG1)
hydrolase activity, acting on glycosyl bonds (OGG1) nucleolus (OGG1) nucleus (OGG1)
Anatomy Link Frequency
Caco-2 4
OGG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 17 99.18 Very High Very High Very High
Somatostatin 3 98.16 Very High Very High Very High
agonist 1 48.92 Quite Low
ischemia 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 40 63.44 Quite High
Apoptosis 24 39.64 Quite Low
Death 6 33.88 Quite Low
Inflammatory Bowel Disease 14 5.00 Very Low Very Low Very Low
Parkinson's Disease 12 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Reperfusion Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, pre-incubation of Caco-2/15 cells with BHT prevented the decline in OGG1 expression.


Negative_regulation (prevented) of Gene_expression (expression) of OGG1 in Caco-2
1) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910735 Disease Relevance 0.06 Pain Relevance 0
However, pre-incubation of Caco-2/15 cells with BHT prevented the decline in OGG1 expression.


Negative_regulation (decline) of Gene_expression (expression) of OGG1 in Caco-2
2) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910735 Disease Relevance 0.06 Pain Relevance 0
In somatostatin (SRIF) antiserum (anti-SRIF; 0.5 ml, iv)-treated adult diestrous animals, CLON induced a significant GH surge that was suppressed by oGH preinjection.
Negative_regulation (suppressed) of Gene_expression (preinjection) of oGH associated with somatostatin and clonidine
3) Confidence 0.12 Published 1989 Journal Endocrinology Section Abstract Doc Link 2571494 Disease Relevance 0 Pain Relevance 1.26

General Comments

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