INT268944

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) cytoskeleton (Crmp1)
plasma membrane (Ros1) microtubule organizing center (Crmp1) cytoplasm (Crmp1)
Ros1 (Rattus norvegicus)
Crmp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 8 49.04 Quite Low
Dopamine 1 30.04 Quite Low
Hippocampus 7 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 10 82.44 Quite High
Stress 9 54.48 Quite High
Drug Induced Neurotoxicity 3 43.88 Quite Low
Apoptosis 37 22.28 Low Low
Neurodegenerative Disease 14 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that METH-induced mitochondrial fragmentation is mediated by ROS, which indirectly regulates the oligomerization and translocation of Drp1 from the cytosol to the mitochondria.
ROS Regulation (regulates) of Localization (translocation) of Drp1
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2677674 Disease Relevance 0.21 Pain Relevance 0

General Comments

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