INT269004

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Context Info
Confidence 0.56
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cthrc1) cytoplasm (Cthrc1)
Anatomy Link Frequency
extracellular matrix 1
Cthrc1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 7 100.00 Very High Very High Very High
cytokine 6 37.12 Quite Low
Inflammation 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 58 99.84 Very High Very High Very High
Cancer 63 77.12 Quite High
Metaplasia 2 73.64 Quite High
Atrophic Gastritis 3 72.72 Quite High
Gastritis 7 71.92 Quite High
Apoptosis 3 70.40 Quite High
Malignant Neoplastic Disease 10 66.72 Quite High
Sprains And Strains 42 60.08 Quite High
Alcohol Addiction 1 54.96 Quite High
Metastasis 7 49.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although multiple primers and pair combinations were tried, PCR products could not be obtained for Scrt1, Cthrc1, Myo1d, or Atf1.


Neg (not) Gene_expression (obtained) of Cthrc1
1) Confidence 0.56 Published 2006 Journal Mamm Genome Section Body Doc Link PMC2677977 Disease Relevance 0.17 Pain Relevance 0
Our study identified a large number of genes associated with the extracellular matrix (SPARC, SERPINH1/HSP47, COL1A1, COL1A2, COL4A1, MMP3, TIMP1, PRSS2, CDH3, SPP1, IL8, CTSB, LUM, CEACAM, CTHRC1, SULF1, ASPN, SPON2 and CLDN18) and chemokine activity, to be differentially expressed in gastric cancers.
Gene_expression (expressed) of CTHRC1 in extracellular matrix associated with chemokine and stomach cancer
2) Confidence 0.07 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC3004887 Disease Relevance 1.28 Pain Relevance 0.05

General Comments

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