INT269104

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Context Info
Confidence 0.19
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.25
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (AOX1)
Anatomy Link Frequency
proximal 1
teeth 1
AOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 3 95.08 Very High Very High Very High
ischemia 3 93.12 High High
backache 15 89.10 High High
cocaine 6 86.92 High High
Angina 6 83.76 Quite High
Pain 3 43.36 Quite Low
nud 6 40.56 Quite Low
imagery 12 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 12 99.96 Very High Very High Very High
Marfan Syndrome 129 99.64 Very High Very High Very High
Hypertension 33 99.50 Very High Very High Very High
Overactive Bladder 3 98.28 Very High Very High Very High
Stress 9 97.56 Very High Very High Very High
Cv General 4 Under Development 12 95.08 Very High Very High Very High
Pressure Volume 2 Under Development 9 94.06 High High
Myocardial Infarction 24 92.20 High High
Disease 6 90.64 High High
Low Back Pain 15 89.10 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypotension and shock in AoD patients can be caused by acute aortic regurgitation, aortic rupture, cardiac tamponade and left ventricular systolic dysfunction.11 Hypotension/shock, absence of chest/back pain on presentation and branch involvement have previously been identified to be associated with increased risk of in-hospital mortality in patients with type B AoD.12 Hypertension is more common in patients with distal dissection, whereas hypotension occurs mostly in proximal dissection.13,14 Although previous reports on the surgical management of AoD showed higher risk of developing type A AoD and a fatal outcome in patients with Marfan syndrome,15 our study failed to demonstrate statistical significance regarding the higher rate of type A AoD, increased recurrence and mortality rate in young patients with Marfan syndrome.
Positive_regulation (increased) of AoD in proximal associated with shock, aortic rupture, recurrence, backache, pressure volume 2 under development, cv unclassified under development, hypertension, marfan syndrome and aortic valve insufficiency
1) Confidence 0.19 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2678699 Disease Relevance 1.98 Pain Relevance 0.17
Our finding is comparable with previous study that patients with Marfan syndrome tended to present with AoD at younger age and were not more hypertensive than those patients who had AoD but not Marfan syndrome.10 In addition, we found that acute AoD was developed at lower BP in patients with Marfan syndrome.
Neg (not) Positive_regulation (had) of AoD associated with hypertension and marfan syndrome
2) Confidence 0.19 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2678699 Disease Relevance 0.75 Pain Relevance 0
AoD has been reported to be triggered by working, eating, drinking, defecation, urination, sports, housework, driving, walking, taking a bath, getting up from bed, dressing or undressing, brushing teeth, and numerous other examples of emotional stress.18 Anecdotal observations revealed weight lifting to be a triggering event of AoD.19-21 In addition, the use of cocaine or "crack" is an another association with AoD in young individuals.22 Hypertension and tachycardia induced by the pharmacologic effects of cocaine are speculated to be the causes of development and propagation of AoD.23 Our study identified that sexual intercourse and forceful coughing were two additional triggers for the onset of acute AoD in young patients.
Positive_regulation (triggered) of AoD in teeth associated with stress, heart rate under development, hypertension, overactive bladder and cocaine
3) Confidence 0.18 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2678699 Disease Relevance 1.53 Pain Relevance 0.23

General Comments

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