INT269109

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.08
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.90
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp2b10)
Anatomy Link Frequency
cartilage 1
neurons 1
Cyp2b10 (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 41 97.84 Very High Very High Very High
Pain 2 10.64 Low Low
cytokine 7 5.00 Very Low Very Low Very Low
drug abuse 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
opiate 3 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 157 100.00 Very High Very High Very High
Dementia 13 99.98 Very High Very High Very High
Chondrosarcoma 104 99.84 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 24 99.54 Very High Very High Very High
Malignant Neoplastic Disease 18 99.40 Very High Very High Very High
Recurrence 2 89.04 High High
Lymphatic System Cancer 3 77.60 Quite High
Skin Cancer 6 77.08 Quite High
Apoptosis 14 71.12 Quite High
Breast Cancer 4 45.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Martin's group has also explored the role of telomerase combined with the loss of tumor suppressor protein p16 as a means of malignant transformation of cartilage neoplasms and found that these two mutations in combination lead to a more aggressive and invasive phenotype in vitro [17].
Negative_regulation (loss) of p16 in cartilage associated with malignant neoplastic disease and cancer
1) Confidence 0.08 Published 2011 Journal Sarcoma Section Body Doc Link PMC3018623 Disease Relevance 1.23 Pain Relevance 0
Loss of Tumor Suppressor p16 in Chondrosarcoma Leads to Radioresistance
Negative_regulation (Loss) of p16 associated with chondrosarcoma and cancer
2) Confidence 0.07 Published 2011 Journal Sarcoma Section Body Doc Link PMC3018623 Disease Relevance 1.39 Pain Relevance 0
Cocaine effects may be important in vivo since the neurons of drug abusing patients with HIV-1 associated dementia displayed gp120, p24 and Nef.



Negative_regulation (displayed) of p24 in neurons associated with dementia, acquired immune deficiency syndrome or hiv infection and cocaine
3) Confidence 0.02 Published 2008 Journal The Open Virology Journal Section Abstract Doc Link PMC2678818 Disease Relevance 0.27 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox