INT269190

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) plasma membrane (Ephb1)
molecular_function (Ceacam3) cellular_component (Ceacam3) biological_process (Ceacam3)
Ephb1 (Rattus norvegicus)
Ceacam3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 28 100.00 Very High Very High Very High
nMDA receptor 15 100.00 Very High Very High Very High
Pain 19 99.36 Very High Very High Very High
Arthritis 15 99.16 Very High Very High Very High
Glutamate 1 66.52 Quite High
anesthesia 1 16.40 Low Low
nMDA receptor antagonist 11 5.00 Very Low Very Low Very Low
Anterior cingulate cortex 8 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 19 99.36 Very High Very High Very High
Arthritis 15 99.16 Very High Very High Very High
Nociception 1 78.96 Quite High
Paralysis 1 29.52 Quite Low
Stroke 1 19.04 Low Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ERK activation also increases NMDA receptor function in the CeA, but PKC does not seem to be involved [18].
Positive_regulation (activation) of ERK Positive_regulation (increases) of CeA associated with nmda receptor and amygdala
1) Confidence 0.03 Published 2009 Journal Mol Pain Section Body Doc Link PMC2679723 Disease Relevance 0.66 Pain Relevance 1.12

General Comments

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