INT269211

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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SNAI1, CDH1) endosome (CDH1) cell adhesion (CDH1)
Golgi apparatus (CDH1) plasma membrane (CDH1) nucleus (SNAI1)
Anatomy Link Frequency
mesenchymal cells 2
SNAI1 (Homo sapiens)
CDH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 82.80 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pathologic Processes 1 87.76 High High
Cancer 73 85.20 High High
Internal Fibrosis 1 83.28 Quite High
Carcinoma 5 71.36 Quite High
Aggression 1 63.76 Quite High
Malignant Neoplastic Disease 1 58.28 Quite High
Disease 3 54.76 Quite High
Recurrence 3 51.36 Quite High
Colon Cancer 14 47.88 Quite Low
Metastasis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The current working model supposes that Snail1 is required for triggering E-cadherin down-regulation and EMT but not for silencing E-cadherin gene expression in mesenchymal cells [3].
Snail1 Neg (not) Positive_regulation (required) of Gene_expression (expression) of E-cadherin in mesenchymal cells
1) Confidence 0.40 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680015 Disease Relevance 0.73 Pain Relevance 0.04

General Comments

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