INT269213

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SNAI1, CDH1) endosome (CDH1) cell adhesion (CDH1)
Golgi apparatus (CDH1) plasma membrane (CDH1) nucleus (SNAI1)
Anatomy Link Frequency
epithelial cells 3
SNAI1 (Homo sapiens)
CDH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 9.80 Low Low
cytokine 1 8.40 Low Low
palliative 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 100.00 Very High Very High Very High
Cancer 73 96.44 Very High Very High Very High
Ovarian Cancer 2 92.32 High High
Endometroid Carcinoma 1 90.16 High High
Colon Cancer 14 89.68 High High
Skin Cancer 1 84.00 Quite High
Adenocarcinoma 2 80.36 Quite High
Metastasis 6 65.68 Quite High
Recurrence 3 44.64 Quite Low
Breast Cancer 1 20.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that this different association of Snail1 with clinicopathologic parameters is due to the cell-specific expression of other proteins necessary for the repression by this factor of key targets in epithelial cells, such as E-cadherin.
Snail1 Binding (association) of in epithelial cells Positive_regulation (due) of Gene_expression (expression) of E-cadherin in epithelial cells associated with repression
1) Confidence 0.37 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680015 Disease Relevance 1.03 Pain Relevance 0

General Comments

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