INT269249

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ptk2, Src) nucleus (Ptk2, Src) cytoskeleton (Ptk2, Src)
plasma membrane (Ptk2, Src) kinase activity (Ptk2, Src) mitochondrion (Src)
Ptk2 (Mus musculus)
Src (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 82.40 Quite High
imagery 15 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 7 100.00 Very High Very High Very High
Cancer 62 94.52 High High
Breast Cancer 22 62.16 Quite High
Metastasis 62 55.24 Quite High
Recurrence 1 16.16 Low Low
Osteolysis 4 5.00 Very Low Very Low Very Low
Advanced Or Metastatic Breast Cancer 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, it has been shown that hydrogen peroxide, released as a consequence of LOX mediated catalysis, triggers the phosphorylation and activation of two key signal transduction pathway activators: Src and focal adhesion kinase (FAK).
FAK Positive_regulation (activators) of Phosphorylation (phosphorylation) of Src associated with adhesions
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680032 Disease Relevance 0.93 Pain Relevance 0.04

General Comments

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