INT269259

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.62
First Reported 2009
Last Reported 2009
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.97
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mecr) mitochondrion (Mecr) oxidoreductase activity (Mecr)
nucleus (Mecr)
Anatomy Link Frequency
cardiac myocytes 1
hearts 1
Mecr (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 140 99.96 Very High Very High Very High
Heart Rate Under Development 6 98.44 Very High Very High Very High
Cardiomyopathy 10 84.32 Quite High
Cancer 4 81.00 Quite High
Fatigue 2 78.16 Quite High
Parkinson's Disease 2 56.24 Quite High
Embryonic Lethality 2 33.28 Quite Low
Mitochondrial Myopathies 2 30.00 Quite Low
Natriuresis 4 5.00 Very Low Very Low Very Low
Hypertrophy 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When these transgenic lines are available, we are going to addresses several issues: (i) how the expression levels of Mecr are regulated in vivo; (ii) the molecular and physiological mechanisms of the cardiac phenotype of the Mecr transgenic mice; (iii) whether the poor exercise performance of the Mecr transgenic mice is solely because of the overexpression of Mecr in cardiac myocytes.
Spec (whether) Regulation (regulated) of Mecr in cardiac myocytes associated with targeted disruption
1) Confidence 0.62 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680037 Disease Relevance 1.05 Pain Relevance 0
Noteworthily, the levels of mRNAs of heart failure mark genes and their relevant transcription factors did not show significant changes in Mecr transgenic hearts compared to wild type controls.
Neg (not) Regulation (changes) of Mecr in hearts associated with targeted disruption and heart rate under development
2) Confidence 0.39 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680037 Disease Relevance 0.91 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox