INT269416

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ISM2, ISM2) nucleolus (ISM2, ISM2) nucleus (ISM2, ISM2)
cell differentiation (RAB5A) plasma membrane (RAB5A) GTPase activity (RAB5A)
Anatomy Link Frequency
tail 2
ISM2 (Homo sapiens)
RAB5A (Homo sapiens)
ISM2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 106 87.16 High High
imagery 7 75.72 Quite High
Dopamine 1 72.00 Quite High
dopamine receptor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low
Stroke 3 5.00 Very Low Very Low Very Low
Thrombosis 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
307 suggests that while the C-tail is not essential for Rab5a interaction, it appears to have a role in regulating further trafficking of the hIP from the Rab5-early endosomes, perhaps to other Rab-containing transport vesicles, preventing it from recycling to the plasma membrane in a dysregulated manner.
C-tail Neg (not) Positive_regulation (essential) of Rab5a Neg (not) Binding (interaction) of C-tail in tail
1) Confidence 0.00 Published 2008 Journal Biochim Biophys Acta Section Body Doc Link PMC2680976 Disease Relevance 0 Pain Relevance 0.16

General Comments

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