INT269666

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.38
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (RHOA) mitochondrion (RHOA) cell morphogenesis (RHOA)
intracellular (RHOA) GTPase activity (RHOA) cytoplasm (RHOA)
RHOA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 65 77.36 Quite High
antagonist 5 12.16 Low Low
imagery 10 5.00 Very Low Very Low Very Low
Angina 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 15 86.56 High High
Targeted Disruption 20 68.08 Quite High
Atherosclerosis 15 60.72 Quite High
Hypertension 20 59.12 Quite High
Thrombosis 15 58.56 Quite High
Disease 10 46.72 Quite Low
Muscular Spasm 5 42.52 Quite Low
Coronary Artery Disease 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 5 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
independently or indeed differentially modulate RhoA activation and downstream signaling, there is substantial evidence that the TP?
Regulation (modulate) of Gene_expression (activation) of RhoA
1) Confidence 0.32 Published 2008 Journal Cellular Signalling Section Body Doc Link PMC2681257 Disease Relevance 0.18 Pain Relevance 0.04
independently contribute to U46619-induced RhoA activation and signaling in 1° h.AoSMCs and to ascertain whether the inhibitory effects of NO and/or Cicaprost may directly target TP?
Regulation (contribute) of Gene_expression (activation) of RhoA
2) Confidence 0.32 Published 2008 Journal Cellular Signalling Section Body Doc Link PMC2681257 Disease Relevance 0.07 Pain Relevance 0.06
contribute to RhoA activation, our findings support the hypothesis that TP?
Regulation (contribute) of Gene_expression (activation) of RhoA
3) Confidence 0.32 Published 2008 Journal Cellular Signalling Section Abstract Doc Link PMC2681257 Disease Relevance 0 Pain Relevance 0
independently regulated RhoA activation and signaling in clonal cells over-expressing TP?
Regulation (regulated) of Gene_expression (activation) of RhoA
4) Confidence 0.32 Published 2008 Journal Cellular Signalling Section Abstract Doc Link PMC2681257 Disease Relevance 0 Pain Relevance 0
qQ209 l,D277N), significantly impaired U46619-mediated RhoA activation through both TP?
Regulation (through) of Gene_expression (activation) of RhoA
5) Confidence 0.32 Published 2008 Journal Cellular Signalling Section Body Doc Link PMC2681257 Disease Relevance 0.14 Pain Relevance 0

General Comments

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