INT269719

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 2.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

FAIM3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Buprenorphine 176 99.70 Very High Very High Very High
Morphine 16 98.28 Very High Very High Very High
opioid receptor 4 96.72 Very High Very High Very High
transdermal 66 91.92 High High
withdrawal 2 86.48 High High
analgesia 16 81.64 Quite High
Analgesic 27 77.92 Quite High
Opioid 38 74.52 Quite High
tolerance 5 73.36 Quite High
Breakthrough pain 4 70.20 Quite High
Disease Link Frequency Relevance Heat
Substance Withdrawal Syndrome 2 86.84 High High
Pain 79 70.20 Quite High
Constipation 2 46.32 Quite Low
Respiratory Failure 25 31.04 Quite Low
Neuropathic Pain 15 5.00 Very Low Very Low Very Low
Cancer 11 5.00 Very Low Very Low Very Low
Sleep Disorders 9 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Cognitive Disorder 7 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Buprenorphine was unable to trigger mu receptor internalization because it has a low efficacy for activating G proteins.
Neg (unable) Positive_regulation (trigger) of Localization (internalization) of mu receptor associated with buprenorphine
1) Confidence 0.17 Published 2008 Journal Clinical Interventions in Aging Section Body Doc Link PMC2682375 Disease Relevance 0.22 Pain Relevance 2.36

General Comments

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