INT269759

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DMD) extracellular space (PTH) extracellular region (PTH)
cytoskeleton (DMD) nucleus (DMD) cytoplasm (DMD)
PTH (Homo sapiens)
DMD (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 3 62.80 Quite High
fibrosis 110 36.64 Quite Low
alcohol 2 32.04 Quite Low
backache 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 31 98.96 Very High Very High Very High
Osteoporosis 64 96.16 Very High Very High Very High
Hip Fractures 5 86.48 High High
Bone Cancer 25 37.48 Quite Low
Cystic Fibrosis 110 36.64 Quite Low
Aseptic Necrosis Of Bone 2 20.04 Low Low
Reprotox - General 2 5 19.76 Low Low
Fracture Healing 1 19.44 Low Low
Osteogenic Sarcomas 8 5.00 Very Low Very Low Very Low
Pulmonary Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, studies in both men and women have clearly shown that bisphosphonates impair the ability of teriparatide or PTH (1–84) to increase BMD (Neer et al 2002; Black et al 2003; Finkelstein et al 2003).
PTH Positive_regulation (increase) of BMD
1) Confidence 0.06 Published 2008 Journal Clinical Interventions in Aging Section Body Doc Link PMC2682396 Disease Relevance 0.09 Pain Relevance 0
Human studies show increase in BMD similar to that with PTH, but without significant hypercalcemia or other adverse effects as observed with PTH.
PTH Positive_regulation (increase) of BMD associated with hypercalcemia
2) Confidence 0.01 Published 2011 Journal Journal of Osteoporosis Section Body Doc Link PMC3010683 Disease Relevance 0.29 Pain Relevance 0.03

General Comments

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