INT269893

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Context Info
Confidence 0.18
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pcna) intracellular (Pcna) DNA binding (Pcna)
transcription factor binding (Pcna) cytoplasm (Pcna)
Pcna (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 3 76.60 Quite High
colic 1 5.00 Very Low Very Low Very Low
neuralgia 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 15 90.24 High High
Cancer 23 77.20 Quite High
INFLAMMATION 3 76.60 Quite High
Apoptosis 33 76.56 Quite High
Death 16 75.76 Quite High
Hypoglycemia 1 75.32 Quite High
Colon Cancer 1 65.80 Quite High
Breast Cancer 1 56.76 Quite High
Repression 7 49.28 Quite Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies have shown that post-mitotic cells can reenter the cell cycle by blocking the expression of cyclin-dependent kinase inhibitors, supporting a role for this protein family in maintaining the balance between quiescence and proliferation [54].
Negative_regulation (blocking) of Gene_expression (expression) of cyclin
1) Confidence 0.18 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0.20 Pain Relevance 0
Western blot analyses indicated that [6]-gingerol decreased both Cyclin A and Cyclin-dependent kinase (Cdk) expression.
Negative_regulation (decreased) of Gene_expression (expression) of Cyclin
2) Confidence 0.01 Published 2006 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2687755 Disease Relevance 0.67 Pain Relevance 0.04

General Comments

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