INT269921

Context Info Confidence 0.12 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

transport (Smad3, Scn4a) intracellular (Smad3) DNA binding (Smad3) protein complex (Smad3) transmembrane transport (Scn4a) cytoplasm (Smad3)

Anatomy Link Frequency MH1 1 Smad3 (Mus musculus) Scn4a (Mus musculus)

Pain Link Frequency Relevance Heat ketamine 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Repression 7 5.00 Targeted Disruption 4 5.00 Hyperplasia 2 5.00 Injury 2 5.00 Exsanguination 1 5.00 Apoptosis 1 5.00 Breast Cancer 1 5.00 Cancer 1 5.00 Hypoglycemia 1 5.00 Colon Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

While both the MAD homology domains (MH1 and MH2) of Smad3 interacted with Sox17 at low stringency binding conditions (data not shown), Smad3 1–145 did not bind to Sox17 under higher stringency conditions (Fig. 7B).

Smad3 Binding (interacted) of MH2 in MH1

1) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0

General Comments

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