INT269947

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Sox17, Atxn1) nucleoplasm (Atxn1) RNA binding (Atxn1)
DNA binding (Sox17) transcription factor binding (Sox17) cytoplasm (Atxn1)
Sox17 (Mus musculus)
Atxn1 (Mus musculus)
Pain Link Frequency Relevance Heat
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 19.36 Low Low
Apoptosis 3 16.16 Low Low
Repression 21 5.00 Very Low Very Low Very Low
Hyperplasia 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Exsanguination 3 5.00 Very Low Very Low Very Low
Breast Cancer 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Hypoglycemia 3 5.00 Very Low Very Low Very Low
Colon Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these studies show that the Sox17 induced Sca-1 expression in cells near the BADJ that coexpressed CCSP but not proSP-C, while the Sca-1 expressing cells induced in the alveolar region expressed neither CCSP nor proSP-C.
Sox17 Positive_regulation (induced) of Gene_expression (expression) of Sca-1
1) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0
During the induction of progenitor cell behavior, Sox17 increased expression of Sca-1, a progenitor cell marker, and stimulated cell proliferation in association with altered expression of cell cycle regulatory genes.
Sox17 Positive_regulation (increased) of Gene_expression (expression) of Sca-1
2) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0
During initiation of progenitor cell behavior, Sox17 induced proliferation and increased the expression of the progenitor cell marker Sca-1 and genes involved in cell cycle progression.
Sox17 Positive_regulation (increased) of Gene_expression (expression) of Sca-1
3) Confidence 0.07 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0

General Comments

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