INT269958

Context Info Confidence 0.25 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.30 Pain Relevance 0

nucleus (Sox17, Cdkn2b, Smad3) DNA binding (Sox17, Smad3) cytoplasm (Cdkn2b, Smad3) transcription factor binding (Sox17, Smad3) transport (Smad3) intracellular (Smad3)

Sox17 (Mus musculus) Cdkn2b (Mus musculus) Smad3 (Mus musculus)

Pain Link Frequency Relevance Heat ketamine 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Repression 7 85.52 Targeted Disruption 4 5.00 Hyperplasia 2 5.00 Injury 2 5.00 Exsanguination 1 5.00 Apoptosis 1 5.00 Breast Cancer 1 5.00 Cancer 1 5.00 Hypoglycemia 1 5.00 Colon Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Sox17 significantly decreased Smad3 binding to the p15 promoter (Fig. 7F).

Sox17 Negative_regulation (decreased) of p15 Binding (binding) of Smad3

1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0.30 Pain Relevance 0

General Comments

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