INT269997

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.33
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (TNFRSF1B) extracellular region (TNFRSF1B) plasma membrane (TNFRSF1B)
Anatomy Link Frequency
immune system 2
lungs 2
TNFRSF1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 90 89.44 High High
fibrosis 30 82.32 Quite High
ischemia 18 81.24 Quite High
Crohn's disease 1 64.88 Quite High
rheumatoid arthritis 2 64.08 Quite High
cytokine 76 58.76 Quite High
depression 25 50.00 Quite Low
Central nervous system 3 17.64 Low Low
cva 24 5.00 Very Low Very Low Very Low
Serotonin 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 25 99.82 Very High Very High Very High
Hypothermia 138 99.30 Very High Very High Very High
Death 10 98.48 Very High Very High Very High
Hemorrhagic Shock 18 91.20 High High
INFLAMMATION 91 89.44 High High
Appetite Loss 1 84.60 Quite High
Pulmonary Fibrosis 4 82.32 Quite High
Cv Unclassified Under Development 16 81.24 Quite High
Obesity 19 80.08 Quite High
Occupational Lung Diseases 54 79.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B did not take place in the lungs of double (p55p75) TNF?
Neg (not) Regulation (take) of Gene_expression (lungs) of p75 in lungs
1) Confidence 0.44 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682759 Disease Relevance 0.24 Pain Relevance 0.10
TNF-R p55 is expressed in most tissues, whereas expression of TNF-R p75 is highly regulated and typically found in cells of the immune system.
Regulation (regulated) of Gene_expression (expression) of TNF-R p75 in immune system
2) Confidence 0.09 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687935 Disease Relevance 1.30 Pain Relevance 0.30
Hypothermia also suppresses apoptosis by down regulating expression of TNF receptor (TNFR1) [102] and its associated pro-death ligand, apoptosis stimulating fragment (Fas) protein.
Regulation (regulating) of Gene_expression (expression) of TNF receptor associated with hypothermia, apoptosis and death
3) Confidence 0.01 Published 2009 Journal Scand J Trauma Resusc Emerg Med Section Body Doc Link PMC2806855 Disease Relevance 1.80 Pain Relevance 0.20

General Comments

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