INT270000

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Context Info
Confidence 0.73
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRAK1) signal transduction (IRAK1) plasma membrane (IRAK1)
nucleus (IRAK1) kinase activity (IRAK1) cytoplasm (IRAK1)
Anatomy Link Frequency
T cells 1
IRAK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 20 99.98 Very High Very High Very High
rheumatoid arthritis 69 83.44 Quite High
Inflammation 76 67.20 Quite High
metalloproteinase 12 54.56 Quite High
fibrosis 58 44.52 Quite Low
Osteoarthritis 25 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 2 85.60 High High
Rheumatoid Arthritis 69 83.44 Quite High
Sprains And Strains 6 73.84 Quite High
INFLAMMATION 71 67.20 Quite High
Arthritis 2 56.80 Quite High
Apoptosis 21 48.84 Quite Low
Fibrosis 22 44.52 Quite Low
Cancer 9 40.48 Quite Low
Colon Cancer 2 39.84 Quite Low
Syndrome 9 24.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cytokine group (12 transcripts mRNAs): CCL2, IL1B, IL6, CSF2, CSF3, IFNG, IRAK1, IRAK2, NLRP2, KAT2B, STAT1, and EGR1 (All abbreviations are current Entrez Gene official symbols and official full names are presented in Table S1).
Localization (presented) of IRAK1 associated with cytokine
1) Confidence 0.73 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682759 Disease Relevance 0.22 Pain Relevance 0.16
Cytokine group (12 transcripts mRNAs): CCL2, IL1B, IL6, CSF2, CSF3, IFNG, IRAK1, IRAK2, NLRP2, KAT2B, STAT1, and EGR1 (All abbreviations are current Entrez Gene official symbols and official full names are presented in Table S1).
Localization (group) of IRAK1 associated with cytokine
2) Confidence 0.73 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682759 Disease Relevance 0.20 Pain Relevance 0.11
t, IRAK1 and SOCS1in the differentiation of IL-17 producing T cells.
Localization (differentiation) of IRAK1 in T cells
3) Confidence 0.38 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2950393 Disease Relevance 0.41 Pain Relevance 0.15

General Comments

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