INT270020

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Context Info
Confidence 0.65
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
liver 2


Pain Term Frequency Confidence Heat
fibrosis 32 75.12 Quite High
Inflammation 9 65.12 Quite High
Multiple sclerosis 62 49.32 Quite Low
Demyelination 12 35.12 Quite Low
Endocannabinoid 7 11.96 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Delta-9-tetrahydrocannabinol 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Hyperlipidemia 2 79.20 Quite High
Cystic Fibrosis 32 75.12 Quite High
Wallerian Degeneration 1 74.48 Quite High
INFLAMMATION 9 65.12 Quite High
Disorder Of Lipid Metabolism 16 55.04 Quite High
Demyelinating Disease 84 49.32 Quite Low
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5 45.84 Quite Low
Diabetes Mellitus 1 41.76 Quite Low
Multiple Sclerosis 35 36.72 Quite Low
Graft Vs Host Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Direct SIRT-1-mediated deacetylation of the liver X receptor (LXR)
Gene_expression (deacetylation) of LXR in liver
1) Confidence 0.65 Published 2009 Journal PPAR Research Section Body Doc Link PMC2683338 Disease Relevance 0.07 Pain Relevance 0
This situation is very similar to the effects of a high-glucose diet, which induces, even in the absence of LXR, liver expression of several lipogenic genes, including ACC [52].
Neg (absence) Gene_expression (absence) of LXR in liver
2) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864762 Disease Relevance 0.39 Pain Relevance 0.10

General Comments

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