INT270033

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.34
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod2) oxidoreductase activity (Sod2) mitochondrion organization (Sod2)
DNA binding (Sod2) response to stress (Sod2) cytoplasm (Sod2)
Sod2 (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 24 99.44 Very High Very High Very High
Multiple sclerosis 125 96.16 Very High Very High Very High
Endocannabinoid 14 61.68 Quite High
imagery 26 43.48 Quite Low
Inflammation 28 5.00 Very Low Very Low Very Low
Deafferentation 19 5.00 Very Low Very Low Very Low
cytokine 17 5.00 Very Low Very Low Very Low
Hippocampus 10 5.00 Very Low Very Low Very Low
Central nervous system 9 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 169 99.44 Very High Very High Very High
Multiple Sclerosis 70 98.76 Very High Very High Very High
Disease 98 97.28 Very High Very High Very High
Stress 48 89.76 High High
Hyperglycemia 55 60.92 Quite High
Amyloid Plaque 3 52.24 Quite High
Aging 4 33.52 Quite Low
Toxicity 17 25.00 Low Low
Disorder Of Lipid Metabolism 8 25.00 Low Low
Dementia 3 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Image analysis at the ROIs demonstrated that ROS levels are significantly increased in hyperglycemic mice as compared to the controls and that these levels normalized back to control levels in STZ-treated SOD2 overexpressing mice, Figure 3B.
Regulation (control) of Gene_expression (overexpressing) of SOD2
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956689 Disease Relevance 0.22 Pain Relevance 0
Utilizing the same mouse model, we have previously shown that SOD-2 overexpression did not alter the elevated levels of A?
Neg (not) Regulation (alter) of Gene_expression (overexpression) of SOD-2
2) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2866668 Disease Relevance 0.28 Pain Relevance 0
Ectopic expression studies reveal that even small changes in expression of IDO, HMOX-1, or mitochondrial superoxide dismutase (SOD2) can prevent demyelination in experimental autoimmune encephalomyelitis (EAE) animal models of MS.
Regulation (changes) of Gene_expression (expression) of SOD2 associated with multiple sclerosis and demyelination
3) Confidence 0.32 Published 2009 Journal PPAR Research Section Abstract Doc Link PMC2683338 Disease Relevance 0.92 Pain Relevance 0.31
Ectopic expression studies reveal that even small changes in expression of IDO, HMOX-1, or mitochondrial superoxide dismutase (SOD2) can prevent demyelination in experimental autoimmune encephalomyelitis (EAE) animal models of MS.
Regulation (changes) of Gene_expression (expression) of mitochondrial superoxide dismutase associated with multiple sclerosis and demyelination
4) Confidence 0.28 Published 2009 Journal PPAR Research Section Abstract Doc Link PMC2683338 Disease Relevance 0.91 Pain Relevance 0.31
This change of MnSOD expression was also observed in the SVN but not in the LVN.
Regulation (change) of Gene_expression (expression) of MnSOD
5) Confidence 0.08 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3004876 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox