INT270145

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, IL2) extracellular region (TNF, IL2) signal transduction (TNF)
cell adhesion (IL2) plasma membrane (TNF) intracellular (TNF)
Anatomy Link Frequency
macrophage 1
TNF (Homo sapiens)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 29 41.20 Quite Low
Inflammation 27 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Post herpetic neuralgia 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 24 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Death 17 76.00 Quite High
Aging 103 67.76 Quite High
Apoptosis 31 56.56 Quite High
Infection 23 11.84 Low Low
Viral Infection 3 10.04 Low Low
INFLAMMATION 33 5.00 Very Low Very Low Very Low
Disease 24 5.00 Very Low Very Low Very Low
Nutritional Deficiencies 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, CD28 co-stimulation synergizes with TCR activation and induces IL-2, IL-4, IL-5, tumor necrosis factor (TNF), and granulocyte macrophage colony-stimulating factor production via nuclear factor-kappa B (NF-?
TNF Positive_regulation (induces) of IL-2 in macrophage associated with necrosis and cancer
1) Confidence 0.01 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684090 Disease Relevance 0.53 Pain Relevance 0

General Comments

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