INT270159

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Lck) plasma membrane (Lck) kinase activity (Lck)
cytoplasm (Lck)
Anatomy Link Frequency
LAT 1
Lck (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 4 84.08 Quite High
cytokine 29 60.80 Quite High
Inflammation 27 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Post herpetic neuralgia 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 103 59.16 Quite High
Adhesions 2 56.40 Quite High
Death 17 38.00 Quite Low
Necrosis 1 25.08 Quite Low
Cancer 24 24.72 Low Low
INFLAMMATION 33 5.00 Very Low Very Low Very Low
Apoptosis 31 5.00 Very Low Very Low Very Low
Disease 24 5.00 Very Low Very Low Very Low
Infection 23 5.00 Very Low Very Low Very Low
Nutritional Deficiencies 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following their coalescence the molecule Lck is autophosphorylated, activating ZAP-70 and leading to the activation of linker of activated T cells (LAT).
Positive_regulation (activating) of Lck in LAT
1) Confidence 0.09 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684090 Disease Relevance 0.12 Pain Relevance 0.11

General Comments

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