INT270171

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.91
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lat) plasma membrane (Lat) intracellular (Lat)
Anatomy Link Frequency
LAT 2
Lat (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 4 89.92 High High
cytokine 29 66.64 Quite High
monoamine 2 22.80 Low Low
Inflammation 27 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 180 98.40 Very High Very High Very High
Sprains And Strains 90 96.08 Very High Very High Very High
Eye Infections 2 85.48 High High
Infection 45 77.52 Quite High
Adhesions 2 62.24 Quite High
Aging 103 57.20 Quite High
Death 17 36.04 Quite Low
Herpes Simplex Virus 3 24.92 Low Low
Necrosis 1 23.12 Low Low
Cancer 24 22.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, when the same experimental protocol was applied to rabbits latent with HSV-1 strain KOS, with the goal being to determine whether we could observe a difference in the patterns of enrichment of H3K4me2 associated with the LAT region of KOS following TCIE of latently infected rabbits, we found no significant change (either increase or decrease) in the overall enrichment of H3K4me2 for the LAT 5?
Positive_regulation (increase) of Positive_regulation (enrichment) of LAT 5 associated with cold sores and sprains and strains
1) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 0.94 Pain Relevance 0
Taking into consideration the proximity and spatial arrangement of the IE promoters to the LAT, and specifically to the reactivation critical LAT 5?
Positive_regulation (reactivation) of Positive_regulation (critical) of LAT 5
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 0.84 Pain Relevance 0
Following their coalescence the molecule Lck is autophosphorylated, activating ZAP-70 and leading to the activation of linker of activated T cells (LAT).
Positive_regulation (leading) of Positive_regulation (activation) of LAT in LAT
3) Confidence 0.14 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684090 Disease Relevance 0.12 Pain Relevance 0.12

General Comments

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