INT270236

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.68
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pla2g4a) aging (Pla2g4a) Golgi apparatus (Pla2g4a)
endoplasmic reticulum (Pla2g4a) cytoplasmic membrane-bounded vesicle (Pla2g4a) nucleus (Pla2g4a)
Anatomy Link Frequency
DRG 2
Pla2g4a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Brush evoked pain 19 99.80 Very High Very High Very High
dorsal root ganglion 77 98.48 Very High Very High Very High
Neuropathic pain 13 87.80 High High
Root ganglion neuron 1 75.00 Quite High
Pain 8 66.60 Quite High
Peripheral nerve injury 10 63.04 Quite High
antagonist 3 54.00 Quite High
Spinal cord 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 35 99.80 Very High Very High Very High
Nervous System Injury 44 99.72 Very High Very High Very High
Ganglion Cysts 78 98.48 Very High Very High Very High
Pain 9 66.60 Quite High
Injury 5 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pharmacological inhibition of either p38 or extracellular signal-regulated kinase (ERK) in the injured DRG, which led to suppression of the development of tactile allodynia, did not affect cPLA2 phosphorylation and translocation after nerve injury.
Neg (not) Regulation (affect) of Localization (translocation) of cPLA2 in DRG associated with brush evoked pain, dorsal root ganglion and nervous system injury
1) Confidence 0.24 Published 2009 Journal Mol Pain Section Abstract Doc Link PMC2684092 Disease Relevance 1.68 Pain Relevance 0.93

General Comments

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