INT270256

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK1) mitochondrion (MAPK1) Golgi apparatus (MAPK1)
DNA binding (MAPK1) protein complex (MAPK1) response to stress (MAPK1)
MAPK1 (Homo sapiens)
Mknk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 5 93.20 High High
dorsal root ganglion 77 72.72 Quite High
Pain 8 69.52 Quite High
Brush evoked pain 19 56.64 Quite High
Root ganglion neuron 1 50.00 Quite Low
Neuropathic pain 13 47.92 Quite Low
Neurotransmitter 1 33.12 Quite Low
Peripheral nerve injury 10 21.60 Low Low
Eae 4 7.44 Low Low
Spinal cord 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 78 72.72 Quite High
Pain 9 69.52 Quite High
Nervous System Injury 44 68.24 Quite High
Neuropathic Pain 35 56.64 Quite High
Nociception 1 15.44 Low Low
Inflammatory Pain 1 7.44 Low Low
Injury 5 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that the phosphorylation of these three serine residues may be interactive, because MNK1 is activated by MAPKs such as p38 and extracellular signal-regulated kinase (ERK) [18], and CaMKII modulates ERK activation [19,20].
extracellular signal-regulated kinase Positive_regulation (activated) of MNK1
1) Confidence 0.03 Published 2009 Journal Mol Pain Section Body Doc Link PMC2684092 Disease Relevance 0.52 Pain Relevance 0.27

General Comments

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