INT270341

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Context Info
Confidence 0.57
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.12
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Vcsa1)
Anatomy Link Frequency
smooth muscle 4
Vcsa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 97.76 Very High Very High Very High
substance P 2 97.00 Very High Very High Very High
Inflammation 42 50.00 Quite Low
Pain 1 40.16 Quite Low
antidepressant 1 38.80 Quite Low
Spinal cord 9 5.00 Very Low Very Low Very Low
cINOD 9 5.00 Very Low Very Low Very Low
Kinase C 5 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 8 98.48 Very High Very High Very High
Disorders Of The Lacrimal System 1 98.20 Very High Very High Very High
Natriuresis 2 82.08 Quite High
Reprotox - General 2 288 68.16 Quite High
Diabetes Mellitus 118 59.96 Quite High
Adhesions 9 59.68 Quite High
INFLAMMATION 45 50.00 Quite Low
Pain 1 40.16 Quite Low
Fever 1 36.68 Quite Low
Diarrhoea 4 33.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have recently demonstrated that both gene transfer of Vcsa1 and sialorphin can improve erectile function in the aging rat[2263] suggesting that they play a direct role in the regulating corporal smooth muscle tone.
Positive_regulation (transfer) of Gene_expression (transfer) of Vcsa1 in smooth muscle associated with aging
1) Confidence 0.57 Published 2008 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2684375 Disease Relevance 0.48 Pain Relevance 0.15
The SMR1 protein product of the rat Vcsa1 gene is cleaved into at least two biologically active peptides, sialorphin (QHNPR) and SGP-T (TDIFEGG) (Figure 3).
Positive_regulation (cleaved) of Gene_expression (product) of SMR1 protein
2) Confidence 0.45 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2955637 Disease Relevance 0.16 Pain Relevance 0
We have recently demonstrated that both gene transfer of Vcsa1 and sialorphin can improve erectile function in the aging rat[2263] suggesting that they play a direct role in the regulating corporal smooth muscle tone.
Positive_regulation (transfer) of Gene_expression (transfer) of sialorphin in smooth muscle associated with aging
3) Confidence 0.41 Published 2008 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2684375 Disease Relevance 0.48 Pain Relevance 0.15

General Comments

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